Beta Fulltext view is in preview — article structure may vary. Browse all articles
Contents
Journal of Embryology & Stem Cell Research Research Article 2 min read

Creating the Next Generation Human 2n=44 from Embryonic Stem Cells

Dehghan FK* and Kamalidehghan B*
* Corresponding author
ISSN: 2640-2637  10.23880/jes-16000143  Received: July 09, 2020  Published: August 17, 2020
  views
 3 references
 1 figure
 1 table
PDF
Keywords
Embryonic Stem Cells Chromosomes Zygote
Abstract

A robertsonian translocation does not always produce harmful results. In fact, many mutations are impartial, and some even reach useful traits. For instance, if balanced carriers are parents 13/21 or 14 /21 or 15/21. This is the start of the new generation of human 2n=44 using In vitro fertilization (IVF). In the chromosomes balanced human 14/21 is relatively prevalent. With the proliferation of the cells, 3-type offspring create Second Human Species as follows: Carriers of balanced parents: 45, XY t (13 /21) X 45 XX t (13/21) → Type 1 - human 2n=44. Carriers of balanced parents: 45, XY t (14 /21) X 45 XX t (14/21) → Type 2 - human 2n=44. Carriers of balanced parents: 45, XY t (15 /21) X 45 XX t (15/21) → Type 3 - human 2n=44. Our study suggested that chromosomal evolution is from a chromosomal fusion, playing a significant role in decreasing the ancestral diploid number to the range of values currently seen.

Introduction

Robertsonian rearrangements between rod chromosomes to produce metacentric & submetacentric biarmed chromosomes are a common mechanism of karyotype evolution and occur spontaneously at an appreciable frequency in mammalian tissue culture [1]. We find important clues to the evolution of species from one generation to the next, of the long-term cell culture. The objective of this study is to achieve the evolution of mammals, and predict the emergence of new species.

Methods

In vitro fertilization is a process of fertilization where an egg is combined with sperm outside the body. The process of IVF involves monitoring and stimulating a woman’s ovulation process, removing an ovum from the woman’s ovaries and letting sperm fertilize them after (Retrieved) in a liquid environment in a laboratory.

After the fertilized egg (zygote) undergoes embryo culture for 3-7 days, it is implanted in the same or another woman’s uterus, with the intention of establishing a successful pregnancy [2, 3].

Using this method helps to achieve the evolution of mammals and reach the origin, and predict the emergence of new species. The evolution of humans and all species first begins with the fusion of two acrocentric chromosomes, and the carriers of balanced parents create changes in other species. Centric fusion of two acrocentric chromosomes results in Robertsonian translocation. Comparison of karyotypes was analyzed in 785 primates, species which are indicates that the species began “by the above method” One of the attached documents, for details see Table 1, therefore in my observation shows similar result.

Result

This method is useful for parents carrier of balanced, because they can create two types normal of children, 2n=46 and 2n=44. “By isolating” a new generation of humans can be obtained. In the past, when there was many of births and no information like today, there were exceptions Human has occurred. May by the genius human of history were 2n=44 chromosomes from one of the 3 types created. Human 2n=46 each cell typically contains 5 pairs Acrocentric chromosomes. Human 2n=44 each cell typically contains 3 pairs Acrocentric chromosomes. It is two acrocentric pairs from 2n=46 are fusioned. Create a Second Human Species.

Comparison of karyotypes performed analysis of 785 species of mammals. With many observe that one of the attached documents in confirms the accuracy of our research in the Table 1 & Figure 1.

Figure 1: Diagram schematically creating human 2n=44.
Click to enlarge
Figure 1: Diagram schematically creating human 2n=44.
NFaLepilemurSpeciesauthor’s descriptions2NAMSSYRef.
38The ancestor of the
group
Lepilemur
septentrionalis
The ancestor of the group
andrafiamenensis 138342MA-2
38Start change
Species
one acrocentric pairs
L. septentrionalis 2from 2n=38 are fusioned37323MA-2
38Carrier parents of balanced
Second
Tribe 1L. s. ankaranensis 3species from 2n=3636304MA-2
38Start change
Species
one acrocentric pairs from 2n=36
are fusioned
L. septentrionalis 435285MA-2
38Carrier parents of balanced
Second species from 2n=36
Tribe 2L. s. septentrionalis 534266MA-2

Table 1: Mechanisms of chromosomal changes Species in this group 2n=38 to 2n=34.

NFa = Fundamental arm autosomes; A = Acrocentric chromosomes; MS = metacentric & submetacentric; M = metacentric; S = submetacentric; XY = Sex chromosome. Table 1: Mechanisms of chromosomal changes Species in this group 2n=38 to 2n=34.

References

  1. Kamalidehghan F, Kamalidehghan B (2008) Centric Fusions from Primary Cell Culture of Calf Kidney Applied Chromosomal Evolution, Conservation and Speciation in the Bovidae Family pp: 838-846.
  2. Kolnicki RL (2012) Mammalian species origin and geographical dispersal patterns correlate with changes in chromosome structure, exemplified in lemurs (Madagascar) and bats (worldwide). pp: 1-165.
  3. (2016) Human Genetics.

Cite this article

BibTeX
APA
RIS
@article{dehghan2020,
  title   = {Creating the Next Generation Human 2n=44 from Embryonic
Stem Cells},
  author  = {Dehghan FK* and Kamalidehghan B},
  journal = {Journal of Embryology & Stem Cell Research},
  year    = {2020},
  volume  = {4},
  number  = {2},
  doi     = {10.23880/jes-16000143}
}
Dehghan FK* and Kamalidehghan B (2020). Creating the Next Generation Human 2n=44 from Embryonic
Stem Cells. Journal of Embryology & Stem Cell Research, 4(2). https://doi.org/10.23880/jes-16000143
TY  - JOUR
TI  - Creating the Next Generation Human 2n=44 from Embryonic
Stem Cells
AU  - Dehghan FK* and Kamalidehghan B
JO  - Journal of Embryology & Stem Cell Research
PY  - 2020
VL  - 4
IS  - 2
DO  - 10.23880/jes-16000143
ER  -