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Inflammatory Response in Acute Lung Injury: A Comparison between Intratracheal and Intubation Administration of P. Aeruginosa Lipopolysaccharide

In humans, the hallmark of the acute lung injury (ALI) is a neutrophilic inflammatory response with fibrin-rich proteinaceous exudates containing an array of pro- and anti-infla…

Hopes for Curing Cystic Fibrosis Lung Disease by Non-Viral Gene Therapy

In 2015, interesting results have been published in a Phase IIb clinical trial for the treatment of cystic fibrosis (CF), and in particular for the lung disease occurring in thi…

A Short Report of Parent Reports on Executive Functions

Results from 45 parent respondents indicated a near-significant relationship between children with intellectual disability (ID) and comorbid autism spectrum disorder (ASD) and the…

Dorothy H Andersen, A Woman in Science and her Importance in Cystic Fibrosis

Cystic fibrosis (CF) is the commonest autosomal recessive disease in the Caucasian population, with an incidence of 1 in 2500 newborns. Nowadays the molecular defect underlying the…

Rescue of Inherited Traits for Lethal Respiratory Diseases by Prenatal Gene Editing: More than One Single Gene and One Vector

A paper recently published in Science Translational Medicine [1] reports for the first time a proof of concept study on the potential application of in utero gene editing to face m…