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Bioequivalence & Bioavailability International Journal Research Article 1 min read

Glioma and Extracellular Matrix, A Review on the Integrins as the Receptors of the Extracellular Matrix

Saberi B*
* Corresponding author
ISSN: 2578-4803  10.23880/beba-16000190  Received: March 06, 2023  Published: April 14, 2023
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Keywords
Integrins Glioma Extracellular Matrix Receptors
Abstract

The brain extracellular matrix is a complex structure. The invading tumors like gliomas would interact with the extracellular matrix. There are receptors in the extracellular matrix including Integrins. This brief review tries to point to some important notes about the extracellular matrix and Integrins as a group of receptors in the extracellular matrix which can play the important role in the pathogenesis of gliomas in the brain tissue.

Conclusion

Understanding the basic mechanisms involved in the pathogenesis of gliomas would open new doors to find novel treatment options for such invasive brain tumors. It is of great importance both in basic and clinical settings.

References

  1. Quail DF, Joyce JA (2017) The Micro environmental Landscape of Brain Tumors. Cancer Cell 31(3): 326-341.
  2. Lu P, Weaver VM, Werb Z (2012) The extracellular matrix: A dynamic niche in cancer progression. J Cell Biol 196(4): 395-406.
  3. Danen EHJ (2013) Integrin Signaling as a Cancer Drug Target. ISRN Cell Biol 2013(2): 14.
  4. Quail DF, Joyce JA (2013) Microenvironmental regulation of tumor progression and metastasis. Nat Med 19 (11): 1423-1437.
  5. Onishi M, Ichikawa T, Kurozumi K, Date I (2011) Angiogenesis and invasion in glioma. Brain Tumor Pathol 28(1): 13-24.
  6. Ferrer VP, Neto VM, Mentlein R (2018) Glioma infiltration and extracellular matrix: Key players and modulators. Glia 66(8): 1542-1565.
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@article{saberi2023,
  title   = {Glioma and Extracellular Matrix, A Review on the Integrins as the
Receptors of the Extracellular Matrix},
  author  = {Saberi B},
  journal = {Bioequivalence & Bioavailability International Journal},
  year    = {2023},
  volume  = {7},
  number  = {1},
  doi     = {10.23880/beba-16000190}
}
Saberi B (2023). Glioma and Extracellular Matrix, A Review on the Integrins as the
Receptors of the Extracellular Matrix. Bioequivalence & Bioavailability International Journal, 7(1). https://doi.org/10.23880/beba-16000190
TY  - JOUR
TI  - Glioma and Extracellular Matrix, A Review on the Integrins as the
Receptors of the Extracellular Matrix
AU  - Saberi B
JO  - Bioequivalence & Bioavailability International Journal
PY  - 2023
VL  - 7
IS  - 1
DO  - 10.23880/beba-16000190
ER  -