ISSN: 2578-4676
Authors: Tolstyak Ya F*, Chopyak VV and Yakovlev IG
Introduction: Contemporary transplantology still faces many challanges, in particular due to the lack of living and inanimate donors, compared with the number of recipients; immaturity of immunodiagnostic and other diagnostic tools for the early prevention of acute rejection of graft; toxic effects and other imperfections of immunosuppressants. The Purpose: Of the work is to assess retrospectively аnalysis of recipients after kidney transplantation a family donor in the Lviv Regional Clinical Hospital. Materials and Methods: 89 medical histories of recipients undergoing in-patient treatment in the center of the kidney transplantation and chronic hemodialysis and the department of vascular surgery during the years 2008-2018 (Diagram 1) were analyzed retrospectively. 86 patients undergone one transplantation, 3 more than one. 47 (52.8%) were men and 42 (47. 2%) women. The age of the recipients ranged from 17 to 60 years. The median age of patients was 28.9 ± 1.2 years. Results: HLA-typing was performed in 38 (42.7%) pair of recipients and donors. There were 3 classical loci in 7 (18.9%) patients, 4in 15 (39.5%) recipients, and 5 in 16 (43.3%) patients. HLA matching by degree of match to 36 pairs. The crossmatch donor-recipient reaction was as follows: the absence of dead lymphocytes was observed in the 4donor-recipientpairs; 2 pairs had a dead lymphocyte count of 5%, 9pairs- 10%, 28 pairs - 15%, 45 pairs - 20% and 1 pair- 35%. Cross-matching is typically presented as negative is the 6 donor-recipient pair; indeterminate 37 pairs and positive 46 pairs.
Keywords: Analysis; Kidney Transplantation; Family Donors; Recipients
