ISSN: 2641-9165
Authors: de Melo FTM, Maionchi DO*, de Vasconcelos LG, da Silva JG and Takeuchi KP
Dropper-type dosing systems are responsible for most everyday applications, such as intermittent doses and eye drops, in addition to the preparation of solutions in scientific circles. However, careful evaluation of physical influences such as viscosity, surface tension, temperature, pressure and density related to a dosage it is not taken into account in the leaflets or tables of the drops/mL ratio. The present work presents a review of the available literature to identify and understand the factors present in this type of measurement, as well as the methods and analyzes normally used according to the Pharmacopoeia. Furthermore, in this work it is proposed the use of Computational Fluid Dynamics (CFD) to model and simulate this flow problem in order to predict the dripping phenomenon as a function of the physical conditions of the system. For that, researcher was made on the following topics: drip and dosage-related issues, CFD applied to dosing systems and data collection necessary for modeling and solving of the studied system. It was identified a deficiency in the standardization of dropper instruments. Data of physical characteristics of fluids that can be dosed in droppers were collected. The proposal to use CFD for the simulation and analysis of these cases is valid and used by several works related to laminar flows and the presence of drops.
Keywords: Dropping; Dosing Systems; CFD
