Coadunation and Immixture-EWSR1: SMA3 Fibroblastic Tumour

Authors: Bajaj A*

DOI: 10.23880/hij-16000217

Volume 7, Issue 1

Abstract

EWSR1::SMAD3 fibroblastic tumour is an extremely exceptional, contemporary, benign mesenchymal neoplasm of fibroblastic origin demonstrating varied morphological patterns, characteristic genetic fusions and localized tumour aggression. Tumefaction is predominantly situated upon extremities and exhibits an intense predilection for acral segments. Characteristic diagnostic features appear as a miniature neoplasm confined to acral cutaneous or subcutaneous tissue demonstrating a zonal configuration with hypo-cellular or acellular, hyalinised centric zone and intersecting fascicles of monomorphic, peripheral spindle shaped cells which appear immune reactive to ERG. EWSR1::SMAD3 genetic fusion is observed which assists cogent tumour classification. Neoplasm manifests a sporadic disease emergence

Keywords: Fibroblastic Tumour

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