Nanomedicine & Nanotechnology Open Access (NNOA)

ISSN: 2574-187X

Research Article

Green Synthesis of Iron Oxide Nanoparticles Using Lactobacillus Plantarum Mk-55 and In Vitro Assessment of Cytotoxic Activity

Authors: Yalçınkaya S, Yalcin S* and Çakmakcı Karahan AG

DOI: 10.23880/nnoa-16000242

Abstract

Recently, there has been a significant focus among researchers on developing efficient green chemistry methods for synthesizing metal nanoparticles. The primary objective is to discover an environmentally friendly approach to nanoparticle production. Magnetic nanoparticles have garnered considerable attention in the fields of nanoscience and nanotechnology due to their desirable physicochemical properties, small particle size, and low toxicity. This study aims to synthesize iron oxide nanoparticles using supernatant from Lactobacillus plantarum MK-55 environmentally-friendly process. In the study, iron oxide nanoparticles were synthesized by in situ method. Then, green synthesis was carried out with MK-55 bacterial supernatant. The synthesized nanoparticles were characterized by FTIR and SEM, and cytotoxicity and uptake analyzes were made. The toxic effect of green synthesis nanoparticles on cancer cells was determined according to the results of the study. According to the results obtained, it was observed that the successfully synthesized nanoparticles were effective on cancer cells. However, in vivo studies are needed in further analysis.

Keywords: Nanoparticles; Nanoscience; Nanotechnology

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