Separation of Amphetamine from Captagon Tablets and Analysis by Fourier Transform Infrared Spectroscopy

Authors: Farhat NB*, Shallah SR, Alskafi SK, Abu Adwan YI and Badwan MM

DOI: 10.23880/ijfsc-16000319

Volume 8, Issue 3

Abstract

Effective and rapid detection methods in the field of forensic drug analysis are crucial for reducing overall analysis time and improving reliability. The purpose of this study is to develop a simple and rapid method for the separation of amphetamine from captagon tablets and analysis by means of Fourier transform infrared spectroscopy (FTIR). In this study, the separation of amphetamine using a variety of solvents, including chloroform, Acetonitrile, dichloromethane, methanol and water, were studied. The results obtained show that the separation using a mix of acetonitrile (ACN) with methanol (MeOH) gives a matching percentage close to 97.14% of amphetamine sulfate when compared with the IR spectrum given in the reference (SWGDRUG) library. This method can be used as a confirmatory test for positive results within minutes without false positives

Keywords: Amphetamine; Captagon; FTIR; Qualitative Analysis; Caffeine

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