Journal of Orthopedics & Bone Disorders (JOBD)

ISSN: 2577-297X

ESSAY

A Meta-Analysis of Risk Factors for Stroke after Spinal Surgery

Authors: Liu XW, Hou Y, Shi HY, Zhao T, Shi HY, Shi JG and Shi GD*

DOI: 10.23880/jobd-16000242

Abstract

Background: Perioperative stroke is a rare but serious complication of spinal surgery. However, it has been reported that there are multiple risk factors that contribute to postoperative stroke, but still remains controversial. The aim of this study is to investigate the risk factors of stroke after spinal surgery. Methods: A systematic search of relevant articles is published in PubMed, Embase, Web of Science, Cochrane Library and Clinical Trials databases until August 2022. According to the inclusion and exclusion criteria, two reviewers independently performed literature screening, data extraction and quality assessment of the obtained literature. The Newcastle-Ottawa Scale (NOS) score was used for quality assessment, and STATA 16.0 software was used for meta-analysis. Results: A total of 1706 relevant articles were initially identified and 13 articles were finally included in this study for data extraction and meta-analysis. The meta-analysis showed that advanced age, hypertension and diabetes mellitus were the risk factors for stroke after spinal operation. The OR values (95%CI) of these three factors were 3.36 (1.81, 6.24), 1.61 (1.26, 2.06) and 2.07 (1.23, 3.49) respectively. Conclusions: Advanced age, hypertension and diabetes mellitus are the current risk factors for postoperative cerebrovascular accidents (CVA).

Keywords: Stroke; Spine Surgery; Risk Factors; Advanced Age; Hypertension; Diabetes Mellitus

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