ISSN: 2642-6145
Authors: Yesmin S*, Mishu FA, Mosleh T, Islam A, Sultana T
Reticulocyte count performed on a supravitally stained blood film is an initial and common laboratory method of determining early hematological recovery. This method is rapidly replaced by automated flow cytometry methods which have the advantage of much greater precision before other tests become positive after chemotherapy. A prospective observational study was carried out in the Department of Laboratory Medicine with the Department of Paediatric Haematology and Oncology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh during a period of one year to evaluate the bone marrow recovery in children with acute lymphoblastic leukemia automated reticulocyte analysis over platelet count. A total of fifty patients were enrolled in this study in the remission induction phase. All patients were taken up to 18 years age range with a mean age of 5.5 ± 3.2 years. At the end of the study out of 50 cases, Ret% and Abs ret count showed early recovery in a median of 6 days before the platelet count recovery and concluded that the reticulocyte parameter showed earlier hematopoietic recovery than the platelet count recovery.
Keywords: Platelet Count; Chemotherapy; Remission Induction Phase; Reticulocyte Parameters; Hematological Recovery
