Vaccines & Vaccination Open Access (VVOA)

ISSN: 2578-5044

Mini Review

Future Direction of Neutrophil-based Cancer Immunotherapies

Authors: Khansari N*

DOI: 10.23880/vvoa-16000161

Abstract

Neutrophils are increasingly being investigated for their potential to be used as an immunotherapy for cancer. Research into this area has demonstrated that neutrophils can target and destroy cancer cells and stimulate an immune response to fight the cancer. The next step in this research is to understand how to optimize the use of neutrophils for cancer immunotherapy and to identify potential therapeutic targets. One concern is the possibility of excessive inflammation caused by the activated neutrophils, which could lead to tissue damage and adverse immune reactions in patients. Additionally, there may be a risk of off-target effects where neutrophils attack healthy cells instead of cancerous ones. Investigating these potential side effects and developing strategies to minimize them will be essential for ensuring the safety and efficacy of neutrophil-based therapies in clinical settings.

Keywords: Neutrophil; Inflammation; Cancer; Immunotherapy; Anti-PD1

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