Attention Deficit Hyperactivity Disorder; Genotype-Phenotype Correlates

Authors: Zaky EA*

DOI: 10.23880/pprij-16000365

Volume 8, Issue 3

Abstract

Attention deficit hyperactivity disorder (ADHD) is one of the prevalent neurodevelopmental disorders that starts early in life and have long term impact on all life aspects of the sufferer; academically, socially, psychologically, and occupationally. Accordingly, understanding its multifactorial origin with its correlation to its manifestations and diagnostic criteria is crucial for individualizing the management plan for each case in order to get the best outcome and improve his/her quality of life. This short communication is summarizing the results of some of our researches investigating the genotypic phenotypic profile of ADHD in samples of Egyptian children.

Keywords: Attention Deficit Hyperactivity Disorder; Gene Polymorphism; Dopaminergic System; Folate Metabolism; DRD2 Taq1A Polymorphism; MTHFR Gene Polymorphism

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