The Gorlin Goltz Syndrome: A Case Report

Authors: De Giacomo P*, Federico S, Valenti G and Nistico SP

DOI: 10.23880/cdoaj-16000312

Volume 8, Issue 3

Abstract

A 72-year-old patient comes to our attention for multiple basal cell carcinomas on the face, trunk, upper and lower limbs. The patient had been subjected in the past to the removal of multiple lesions histologically found basal cell carcinomas. The patient's clinical phenotype corresponds to Gorlin Goltz syndrome. The patient is nominated for treatment with Sonidegib, a molecule that binds to a protein that controls the Hedgehog signaling pathway thus reducing the proliferation of cancer cells. The clinical effectiveness of the treatment was considerable.

Keywords: Carcinomas; Gorlin Goltz; Sonidegib; Hedgehog; Proliferation

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