Sidling and Swerve-NUT Carcinoma-Lung

Authors: Bajaj A

DOI: 10.23880/cclsj-16000184

Volume 8, Issue 2

Abstract

NUT carcinoma incriminating pulmonary parenchyma emerges as an aggressive, malignant, poorly differentiated neoplasm characteristically demonstrating genomic rearrangements within NUT gene. The aggressive NUT carcinoma frequently implicates thoracic cavity or aerodigestive tract. However, terminology of NUT midline carcinoma appears obsolete. Neoplasm delineates a nonspecific morphological countenance and demonstrates diffuse architecture composed of monotonous tumour cells permeated with enlarged nuclei, prominent nucleoli and frequently discerned cytoplasmic clearing, intermingled with foci of abrupt keratinization.

Keywords: NUT Carcinoma, Tumour Cells, Chemotherapy, Genomic Fusion

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