ISSN: 2578-465X
Authors: Syeda Amena Saman,Parasappa Bandrakalli, Pavan G
Aim: To assess utility of donor corneas based on analysis of endothelial cells qualitatively and quantitatively. Methods: It was a observational study of donor corneas received at eye bank in a tertiary care centre during period of January 2021 to June 2022. 94 corneoscleral buttons were excised and endothelial cell density and morphology were assessed using specular microscope. Results: With increasing age there was decrease in endothelial cell density seen. A highly significant co-relation was found between age and endothelial cell density. (p<0.001).Endothelial cell count was high in phakic compared to pseudophakic eyes. A highly significant co-relation was found between lens status and endothelial cell density (p<0.001). With increasing age there was decrease in hexagonality of endothelial cells seen. A highly significant co-relation was found between age and hexagonality of endothelial Cells (p<0.001). A highly significant correlation was found between utility of endothelial cells of mean 2018.94, hexagonality of mean 54.39 and co-efficient of variation of mean 34.50. Amongst 94 donor corneas 24.4% were used for optical penetrating keratoplasty, 22.3% for therapeutic purpose, 6.3% for DSEK, 4.2% for DALK and remaining 42.5% for research/practice purpose. Conclusion: Analysis of donor corneas demonstrated that age and pseudophakia as predictor of decrease endothelial cell density. A significant co-relation was found between endothelial cell density and utilization.
Keywords: Donor Corneas; Specular Microscope; Utilization; Optical; Therapeutic Penetrating Keratoplasty
