Humoral and Cellular Immune Response among Kidney Transplant Recipients after COVID-19 Vaccination: A Systematic Review and Meta-Analysis

Authors: Cheepsattayakorn R, Cheepsattayakorn A* and Siriwanarangsun P

DOI: 10.23880/oajprs-16000158

Volume 7, Issue 1

Abstract

A comprehensive search was carried out in mainstream bibliographic databases or Medical Subject Headings, including ScienDirect, PubMed, Scopus, and ISI Web of Science. The search was applied to the articles that were published between 2021 and mid-2023. With strict literature search and screening processes, it yielded 7 articles from 349 articles of initial literature database. A number of previous studies emonstrated that KTRs or non-KTRs with renal failure markedly reduced vaccine response, whereas adaptive protocols of mRNA COVID-19 vaccination or alternative adjuvant vaccines is now not known yet. A recent study revealed that acute kidney injury and mortality could be caused by SARS-CoV-2 (COVID-19) around 50 % and 23 % of the infected KTRs.

Keywords: Cellular; Humoral; Immune; Response; Kidney; Transplant; Hemodialysis; Covid-19; Vaccine; mRNA

View PDF