Formulation and Evaluation of Mouth Dissolving Tablets of Amiodarone

Authors: Karnakar N*, Janardhan A, Hechhu R and Amani P

DOI: 10.23880/oajpr-16000286

Volume 7, Issue 3

Abstract

Mouth dissolving tablets are a vital tool in keeping our children and senior population healthy. Their ease of use and accurate dosing allow advanced patient compliance and further dependable remedial goods. Super disintegrants are the abecedarian element contained in Mouth dissolving tablets and are responsible for their unique capability to snappily disintegrate and dissolve on the face of the lingo without the use of any fresh liquid. In order to determine the most effective type and optimal quantum of super disintegrants for orally disintegrating tablets manufactured by direct contraction, the following tablet parameters were tested hardness, consistence, frangibility, decomposition time, and wetting down time. Three super disintegrants were tested, videlicet Kyron T- 314, Ac- Di- Sol, and Banana Powder and the most effective superdisintegrant was named grounded on the below mentioned studies. From the results attained, it can be concluded that the tablet expression( F3) showed the promising expression also the hardness, frangibility, decomposition time and dissolution rate of set tablets were set up to be respectable according to standard limits.

Keywords: Amiodarone; Kyron T-314, Ac-Di-Sol; Banana Powder and Mouth Dissolving Tablets

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