ISSN: 2573-8771
Authors: Sucharitha A* and Darawadi B
Many studies reveal the relationship between periodontal disease [PD] and cardiovascular diseases [CVD], but their outcome is heterogeneous. This review article is designed to update the basis of understanding the role of periodontal disease in causing cardiovascular events. Studies have investigated a possible link between periodontal diseases and distinctive systemic diseases. Periodontitis is a constant implicit source of infection and has been considered a discrete risk factor for some outcomes like cardiovascular diseases, cerebrovascular diseases, diabetes mellitus complications, chronic obstructive pulmonary disease, pregnancy complications, and osteoporosis, etc. A concise overview has been entailed for atherosclerosis [ATH] its pathophysiology, and the association of periodontal infections as a risk factor for causing atherosclerosis, as the development of ATH is associated with chronic low-grade inflammation moreover, it has been set prior to the development of ischemic heart disease [IHD] and provides a contributing mechanism that ATH may singly contribute or in prime concern with other risk factors to develop ischemic heart disease. Finally, this report summarizes the evidence from epidemiological studies that focus on links that feasibly exist between PD and its role as a risk factor in triggering cardiovascular events and complications of periodontal therapy in patients on anti-thrombotic therapy.
Keywords: Anti-Thrombotic Therapy; Systemic Diseases; Periodontitis; Atherosclerosis; Chronic Inflammation; Periodontal Therapy
