Protein Oxidation is Related to Body Mass Index in Obese Women

Authors: Ana Gabriela da SB , Higachi L , Silva LS , Venturini D , Bonifacio KL and Barbosa DS

DOI: 10.23880/doij-16000111

Volume 1, Issue 2

Abstract

Oxidative stress could be an early event in many pathological conditions, such obesity. Additionally, advanced oxidation protein products (AOPPs) have been reported as the most appropriate parameter for determination of oxidative stress in chronic diseases. The aim of this study were evaluated which oxidative stress biomarker is more related to obesity. This cross sectional evaluated 52 obese women aged (50, 5±1,06 years), and the participants were divided into three groups according to (BMI), G1 (BMI 30-34.9 kg/m2), G2 (BMI 35-39.9 kg/m2) and G3 (BMI40 kg/m2). Biochemical and oxidative stress biomarkers (FOX, AOPP and TRAP) were evaluated. The G3 group presented high levels of C reactive protein (CRP) when compared to G1 group (p<0.05), while serum AOPP levels were significantly increase in G3 group when was compared to G1 and G2 and when G2 was compared to G1 (p<0.05). This study provided that serum levels of AOPP were elevated with increasing BMI and could be regarded as an early biomarker of protein oxidation in obese women.

Keywords: Obesity; Advanced Protein Oxidation; Oxidative Stress

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