ISSN: 2641-9459
Authors: Jalal J, Hedyeh S and Siavash HC*
The coronavirus pandemic has had a major impact on many areas of life, especially health. After the end, it was found that there were numerous persistent symptoms even after no prolonged infection with COVID-19, called post-acute sequalae of Covid-19 (PASC). Symptoms like depression, muscle weakness and fatigue. The information gathering method used for this paper was searching the PubMed, WHO and Google Scholar databases. To achieve the purpose of this review, it was found that there are factors that increase the risk of PASC specific fatigue, such as diabetes and obesity, by increasing the release of pro-inflammatory cytokines. In addition to other psychological factors that occurred during quarantine, such as anxiety, social isolation and the patient’s ability to cope with stressful events and factors beyond the patient’s control while in the hospital, such as: E.g., forced inactivity and bed rest, they all increase muscle wasting and reduce blood flow to skeletal muscles. In conclusion, the mechanisms related to fatigue and its causes are still not clearly understood, but early mobilization has been shown to improve fatigue outcomes of hospitalized patients.
Keywords: Fatigue; Post-Covid 19; Muscle weakness; Post-Covid syndrome; SARS-CoV-2