ISSN: 2639-2127
Authors: Abedi A*, khan FB, Ogunleye AOB, Chermahini SH, and Goderidze T
Healing wounds is an important physiological process in the body followed by trauma, burn injuries, post-surgery complications or different diseases that can damage the skin and tissues. Millions of people struggle with their healing process every year and some of them pass away according to the World Health Organization (WHO). Wound healing is done by different processes that are divided into hemostasis/inflammation phase, proliferation phase, and remodeling phase. The pathophysiology of these processes and the factors affecting them is explained. There are two general factors including systemic and local factors contributing, both explained in this research. Many resources have been reviewed regarding the factors that can enhance the healing process. All the information collected to fulfill one of the important purposes of this research. The enhancing factors which are discussed include therapeutic strategies for enhancing angiogenesis in wound healing like using growth Factors, Non-Growth Factor Protein Delivery, gene, and nucleic Acid-Based therapies for wound angiogenesis. Stem cells therapy one of the most recent topics that is being researched a lot in the wound healing subject and potentially gives hopes to healing enhancement, although more clinical trial and experiments need to be done especially on the human body to be able to get more specific results, hopefully can be proved and used to benefit the people who suffer from this problem around the world.
Keywords: Wound Healing; Wound Angiogenesis; Fast Wound Healing; Growth Factors; Stem Cells Therapy
