ISSN: 2639-2526
Authors: Bajaj A*
Juvenile granulose cell tumour emerges as an exceptionally discerned neoplasm engendered from primitive granulosa cells. Tumefaction configures as a testicular lesion commonly encountered within 6 months of neonatal period. Notwithstanding, tumefaction is comprehensively observed within first decade of life. The neoplasm demonstrates significant morphological variation with occurrence of distinctive solid and follicular tumour patterns. Characteristically, lobular articulations or follicular differentiation are expounded. Notwithstanding, solid or reticular tumour pattern may be challenging to ascertain. Neoplastic cells appear immune reactive to steroidogenic factor 1 (SF1), calretinin, vimentin and inhibin. Tumour cells appear immune non-reactive to alpha fetoprotein (AFP). Malignant metamorphosis remains undocumented.
Keywords: Steroidogenic Factor; Calretinin; Vimentin and Inhibin; paediatric; Abdominal Cavity
