ISSN: 2578-482X
Authors: Farajirad E, Mohazzab Torabi S and Farajirad M*
Introduction: Intracerebral Hematoma (ICH), conventionally associated with vascular causes, is increasingly recognized as the initial presentation of underlying brain tumors. This Narrative review aims to synthesize current literature on the incidence, clinical features, diagnostic challenges, and outcomes associated with ICH as the primary manifestation of brain tumors. Methods: A systematic search across PubMed, Embase, and Cochrane Library databases yielded studies meeting inclusion criteria. These encompassed prospective and retrospective observational studies, case-control investigations, and case series reporting instances where ICH was the initial sign of an underlying brain tumor. Results: Analysis of the selected studies revealed variable incidences of ICH as the first manifestation of brain tumors, with differences across tumor types and patient demographics. Clinical presentations mimicked primary vascular causes, posing diagnostic challenges. Common tumor types included with varying intracranial locations. Treatment strategies ranged from surgery to adjuvant therapies, and outcomes were heterogeneous, influenced by tumor histology, location, and patient characteristics. Discussion: This review highlights the significance of recognizing ICH as an initial sign of brain tumors, emphasizing the need for refined diagnostic approaches and enhanced imaging modalities. Challenges in timely identification underscore the importance of heightened clinical suspicion. The variable outcomes suggest the necessity of tailoring treatment strategies based on tumor characteristics and patient factors, paving the way for future research to optimize interventions in ICH associated with brain tumors.
Keywords: Intra-Cranial Hematoma; Brain Tumours; Melanoma; Lung Small Cell Cancer
