ISSN: 2640-2726
Authors: Emmanuel Ifeanyi Obeagu * and Getrude Uzoma Obeagu
Pediatric severe malaria cases complicated by HIV co-infection present a formidable healthcare challenge, necessitating a nuanced and comprehensive approach to treatment. This review critically examines the efficacy of blood transfusion as a therapeutic intervention in managing severe malaria among pediatric patients co-infected with HIV. We delve into the current state of knowledge, discussing the immunological complexities, potential interactions with antiretroviral therapy, and the inherent challenges associated with this dual burden of disease. Despite the complexities, blood transfusion remains a vital element in addressing severe anemia in pediatric malaria. This review synthesizes existing literature, identifies gaps in knowledge, and proposes avenues for future research to enhance our understanding and optimize treatment strategies for this vulnerable population.
Keywords: Pediatric Malaria; Malaria; HIV; Blood Transfusion; Transfusion Therapy; Pediatric Healthcare; Antiretroviral Therapy
