Bioequivalence & Bioavailability International Journal (BEBA)

ISSN: 2578-4803

Review Article

Transferosomes: A Versatile and Ultradeformable Approach for Targeted Delivery of Anticancer Drugs in the Treatment of Diverse Cancers

Authors: Ali S*

DOI: 10.23880/beba-16000228

Abstract

Nanoparticles, particularly transferosomes, have emerged as promising drug delivery systems in the field of cancer therapy. With their unique properties and high adaptability, transferosomes have shown great potential in improving the targeted delivery of chemotherapeutic drugs, including through transdermal applications. This article provides a comprehensive review of the advancements and applications of transferosomes in cancer therapy and gene delivery; by highlighting the advantages of nanoparticles in cancer treatment, such as their ability to passively target tumors through the enhanced permeation and retention effect. It then focuses on the composition, preparation methods, and advantages of transferosomes over conventional liposomes, including their high stability, high carrier capacity, and ability to deliver drugs to deeper skin layers. The article further explores the applications of transferosomes in cancer therapy. It presents studies that demonstrate the effectiveness of transfersomes in delivering chemotherapeutic drugs, such as doxorubicin hydrochloride, carvedilol, and various natural compounds, for enhanced cancer treatment. Furthermore, it also discusses the use of transfersomes as adjuvant treatments to reduce the risk of cancer recurrence. Overall, this comprehensive review provides valuable insights into the advancements and applications of transferosomes in cancer therapy and gene delivery. The findings emphasize the potential of transferosomes as effective drug carriers, offering improved treatment outcomes and reduced side effect in the fight against cancer

Keywords: Transferosomes; Targeted Therapy; Nanoparticles; Advancements; Cancer

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