Haematology International Journal (HIJ)

ISSN: 2578-501X

Review Article

Anemia and Erythropoietin in HIV: A Multifaceted Review

Authors: Emmanuel Ifeanyi Obeagu* and Getrude Uzoma Obeagu

DOI: 10.23880/hij-16000244

Abstract

Anemia stands as a significant and multifaceted complication in the landscape of HIV, introducing a dynamic interplay of viral, immune, and hematopoietic factors. This comprehensive review navigates the intricate relationship between anemia and erythropoietin in the context of HIV, elucidating the pathogenesis, clinical implications, and evolving treatment paradigms. With an emphasis on the co-infection dynamics, hematopoietic pathogenesis, and the pivotal role of erythropoietin, this review explores the multifaceted nature of anemia in HIV, providing a holistic understanding crucial for effective management. The clinical implications extend beyond the hematological realm, impacting overall health and underscoring the need for tailored treatment strategies. Moreover, this review delves into evolving interventions, including erythropoiesis-stimulating agents and novel therapies, offering insights into the future of anemia management in the complex landscape of HIV. Through a critical examination of current knowledge and identification of research gaps, this review serves as a comprehensive resource for clinicians, researchers, and healthcare providers navigating the intricate terrain of anemia and erythropoietin in the context of HIV infection.

Keywords: Anemia; Erythropoietin; HIV; Hematopoiesis; Co-infection; Pathogenesis; Clinical Implications

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