Open Access Journal of Frailty Science (OAJFS)

Perspective

Challenges in Management of Elderly and Frail Alzheimer’s Disease Patients

Authors: Bharati K*

DOI: 10.23880/oajfs-16000105

Abstract

Alzheimer’s disease is a progressive neurodegenerative disorder, which is responsible for the majority of dementia cases across the globe. Approximately 50 million people are currently suffering from Alzheimer’s worldwide [1]. Disease onset is clinically characterized by cognitive function impairment, which slowly progresses to loss of memory, confusion, behavioral and personality changes, difficulty speaking, loss of ability to live independently, and eventually resulting in a vegetative state [2]. As per the World Health Organization (WHO), the number of people suffering from dementia worldwide is likely to triple by 2050 [3]. In general, Alzheimer’s develops after the age of 65 years, which accounts for 5-10% of this age group. This number increases to 50% in those above 85 years [4]. Notably, the prevalence of Alzheimer’s disease is 19-29% lower in men than in women. Generally, Alzheimer’s patients die within 5-12 years of disease onset [5].

Keywords: Alzheimer’s; Disease; Patients; Caregiving; People

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