An Extensive Analysis of Natural Bioenhancers: A Review

Authors: Salman DS*

DOI: 10.23880/oajpr-16000310

Volume 8, Issue 2

Abstract

The concept of bioavailability enhancer is new to the modern system of medicine. Basically, this concept originated in Ayurveda and being used in this system of medicine since centuries. Chemical substances known as "bioenhancers" work to increase the bioavailability of medications when they are combined with them and do not have a synergistic impact on the drug. The bio‑enhancement leads to reduction in therapeutic dose of principal drug, thus reducing the possibilities of toxicity and side effects of drug, potentiating the efficacy, reducing the resistance, decreasing the requirement of raw material for drug manufacture, and ultimately benefitting to the world economy by reducing the manufacturing cost. A bioenhancers do not introduce its own therapeutic action with the actual active effect at the therapeutic dose used. Herbal bioenhancers are derived from both plant and animal origins. The compounds from plant origin majorly used as a bioenhancer are piperin, naringenin, niaziridin, quercitine, aloe, etc.

Keywords: Bioenhancer; Bioavailability; Biopharmaceutical Classification System; Piperine; Quinidine

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