ISSN: 2642-6145
Authors: Mosleh T*†, Hossain SMZ, Yesmin S* and Akhter S
Background: Asthma is a chronic disease that impacts children’s physical, social and emotional health. Over the past few decades, vitamin D deficiency and insufficiency have increased in the general population and have been associated with respiratory illnesses including asthma. This study compared blood vitamin D levels in asthmatic and non-asthmatic children to investigate if vitamin D insufficiency is linked to different asthma subtypes. Methods and Materials: This cross-sectional study was conducted department of paediatrics of Bangabandhu Sheikh Mujib Medical University from october 2020 to october 2021. Based on predetermined inclusion and exclusion criteria, 60 newly diagnosed children with asthma between the ages of 8 and 18 were enrolled as case. Age and sex matched 30 non-asthmatic children were taken as control. All children’s serum 25(OH)D levels were estimated, and the results between the two groups were compared. In children with asthma, the relationship between vitamin D levels and certain clinical forms of asthma was investigated. Results: Asthmatic and non-asthmatic children had mean ages of 11.32±2.007 and 11.07±1.938, respectively. In the asthma group, 26.7% had intermittent asthma, 30.0% had mild asthma, 28.3% had moderate asthma, and 15.0% had severe asthma. Among them, 23.3% were vitamin D deficient, 53.3% were vitamin D insufficient, and 23.3% were vitamin D sufficient. In the group without asthma, 13.3% had vitamin D deficiency and 40.0% had vitamin D insufficiency. 46.7% possessed a sufficient amount. Vitamin D levels were substantially lower in asthmatic children than in non-asthmatic children (24.77.1 vs. 35.97.6). Serum vitamin D levels had no effect on the various clinical categories of asthma. Conclusion: Children with asthma significantly lower mean serum vitamin D levels when compared with their counterparts without asthma.
Keywords: Asthma; Children; 25 Hydroxy vitamin D
