ISSN: 2578-4803
Authors: Sanyaolu A*
Introduction: Hypertension is one of the most commonly occurring diseases throughout the world. Aspirin is the most recommended drug to prevent cardiovascular diseases in high-risk patients. As this may be true, Aspirin has shown to increase the risk of hypertension. The objective of our study is to see the correlation between Aspirin an NSAID and hypertension within the Anguillan population. Methods: This was a cross-sectional study comprising of males and females in Anguilla above the age of 20 years. Our study’s focus was those that took Aspirin as a self-directed medication or as physician-directed for the prevention of cardiovascular disease. The participants were given a survey to fill out. Surveys were formatted to include demographics, medical, family and social history. Consent for surveys was obtained and permission was granted by the ARB (Anguillan Review Board). Comorbidities were evaluated by self-reporting in the medical history. The goal of this study was to understand whether there was any correlation between Aspirin use and the increased risk of hypertension. Results: Primary outcome was significant with the p-value of 0.0008; however, secondary outcome was not statistically significant (p= 0.7) because whether the Aspirin was prescribed by physician or taken as a self-directed medication does not have influence in the mechanism of action of Aspirin. There was no statistical significance in the male gender between the control and the target groups (p= 0.054). Moreover, statistical significance was noted in female gender between the control and the target group (p= 0.004). Conclusion: The results showed that there was significance in the Blood Pressure of patients who were on Aspirin as compared to those who did not take Aspirin indicating that Aspirin plays a role in hypertension.
Keywords: Hypertension; Aspirin; Nonsteroidal Anti-Inflammatory Drug (NSAID)
