Resveratrol’s Action against Viral Infections

Authors: Dos Santos WM , Farnesi De Assuncao TS , De Matos BS , De Morais Oliveira AC , De Santos Teodoro LC , Okura MH , Manso JC , De Oliveira Silva JC and Paula Rogerio AD

DOI: 10.23880/apct-16000236

Volume 9, Issue 2

Abstract

The biological activity of resveratrol (3,5,4’-trihydroxy-trans-stilbene) has been the subject of extensive study in the treatment of various diseases due to its anti-inflammatory, antioxidant and anticancer activities, as well as its minimal toxicity and side effects. It has been widely accepted that resveratrol also has antiviral activities. In this mini-review, we summarize resveratrol’s antiviral mechanisms. Since viral infections are often accompanied by inflammation, the TLRs/NF-κB signaling pathways are key and common molecular mechanisms for resveratrol to exert anti-inflammatory and antiviral effects.

Keywords: Dengue Virus; COVID-19; Resveratrol; Antiviral

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