ISSN: 2476-2490
Authors: Göktaş SS*
The diagnosis of nonallergic rhinitis, a type of chronic rhinitis, is made by excluding allergic and infectious rhinitis. There is currently no specific method used in diagnosis. It has been determined that rhinitis symptoms occur in nonallergic rhinitis through neuromediators secreted from the TRPV1 receptor located in the nerve endings of sensor c fibers in the nasal mucosa. The initial effect of capsaicin, which acts in this way, is stimulation, while repeated doses are desensitization. Thus, with repeated doses, capsaicin provides control of non-allergic rhinitis symptoms during a long refractory period (lasting several months). Among the reasons why it has not yet come into widespread use are that it causes burning in the nasal mucosa in the first doses, excessive secretion and low comfort, and the minimum effective dose has not yet been clearly determined. In order for capsaicin to become widespread in the treatment of non-allergic rhinitis, studies are needed to determine its effectiveness with low side effects.
Keywords: Intranasal Capsaicin; Treatment; Nonallergic Rhinitis; Patients; Sphenopalatine Ganglion
