ISSN: 2574-8009
Authors: Aye SM, Thein SSK, Bwa AH, Win STS and Win KM*
The hospital-based retrospective descriptive study was done to determine the characteristic and associated factors of MASLD in 817 patients at Yangon Gastrointestinal and Liver Center, Myanmar from April 2017 to Jun 2022. Male and female patients were 427 [52.3%] and 390 [47.7%], respectively. Their steatosis grades were 39.3% in S0, 11.6% in S1, 16.4 in S2 and 32.7% in S3 groups. For fibrosis, F0F1 patients were 89.4%. Twenty-nine patients were F4 stage Cirrhosis. Their mean age at the time of diagnosis was 46.63 [SD ±11.583] years, between 16 to 77 years. Body Mass Index [p<0.001] and Fibroscan-CAP score [p=0.015] were different between sex. Hb A1C, lipid profile, ALT and AST were not statistically different between sex. Steatosis grading [S0, S1, S2 and S3] was associated with BMI [p<0.001] and HbA1C [p=0.003]. Positive correlations were found between Fibroscan-CAP score and age at the time of diagnosis, BMI and HbA1C [p<0.01]. Steatosis grading was associated with HbA1C [p=0.004] and BMI [p<0.001]. Fibrosis staging was associated with HbA1C [p<0.001] and BMI [p=0.007]. Older age patients were more likely to have higher BMI, HbA1C, steatosis grading and fibrosis staging. Overweight and elevated HbA1C patients tend to have higher steatosis grading and fibrosis staging.
Keywords: Fatty Liver; MASLD; Lean MASLD; MASH; Myanmar; Southeast Asia
