ISSN: 2642-6145
Authors: Ghosh S*
Melatonin is an evolutionarily conserved molecule. The chemical structure of melatonin is almost same from protozoans to mammals. Melatonin can exert its functions through its membrane bound receptors (MT1 and MT2). Among the multiple functions regulated by melatonin, the most important is immune-modulation. It is well reported that teleosts are having well developed pineal organ and it is having circulatory level of melatonin. It is also reported by some of the workers that the “snake-head” telost Channa punctatus is having the primitive type of immunogenic cells (if not a well-developed organ) on the dorso-lateral kidney. But, till date a single report is not available regarding the immune-modulatory role of melatonin in teleosts. The present study is aimed to discuss about the developments in this field till date and possible approaches to address the issue.
Keywords: Channa; Crosstalk; Immunity; Melatonin; Strategy
