Otolaryngology Open Access Journal (OOAJ)

ISSN: 2476-2490

Case Report

Angiosarcoma of the Nose- A Rare Case Report Emphasizing Atypical Site and Literature Review

Authors: Rockey Dahiya, M.B.B.S*, Natalie Weiss, M.D, Samip Patel, M.D and Phillip Pirgousis, M.D

DOI: 10.23880/ooaj-16000297

Abstract

Angiosarcoma is a rare and aggressive malignant tumor primarily originating from blood and lymphatic vessels. While it commonly arises from cutaneous sites like the scalp, atypical presentations, such as nasal involvement, pose significant diagnostic challenges. This report presents the case of a 74-year-old male with a rapidly progressive violaceous mass on the nasal sidewall, diagnosed as angiosarcoma. The patient had no history of trauma, radiation, or lymphedema. Biopsy findings, along with immunohistochemical markers such as CD31, CD34, and D2-40, confirmed the diagnosis. The patient underwent subtotal rhinectomy with bilateral selective neck dissection, followed by adjuvant radiotherapy. Post-treatment follow-up showed no recurrence or metastatic disease. This case underscores the importance of considering angiosarcoma as a differential diagnosis in atypical sites and highlights the benefits of early diagnosis and multimodal treatment, which significantly improves survival rates. Further research is needed to establish clear guidelines for surgical margins and comprehensive treatment strategies.

Keywords: Angiosarcoma; Atypical Site; Multimodal Therapy; Radiation Therapy

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