ISSN: 2577-4360
Authors: Witharana C* and Lanerolle Dias MD
Epigenetics is the study of heritable changes in gene expression that do not involve alterations in the DNA sequence itself. These changes can be influenced by various factors, including age, lifestyle, diseases, and diet. Nutrients, notably, play an indispensable role in shaping epigenetic processes through a multitude of mechanisms. This comprehensive review, sheds light on the profound impact of specific nutrients, vitamins such as Folate and B12, plant-based polyphenols such as resveratrol, Omega-3 fatty acids such as docosahexaenoic acid (DHA), and the influence of high-fat diets on the intricate realm of epigenetics. Epigenetics plays a vital role in gene regulation, and nutrients have a significant impact on these epigenetic processes. Understanding these mechanisms can have implications for various health conditions, including cancer, cardiovascular disease, neurodegenerative diseases, and obesity-related disorders.
Keywords: Epigenetics; DNA Methylation; Folate; Vitamin B12; Polyphenols; Omega-3 Fatty Acids
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