The Analysis of Maternal and Fetal Rhesus Status in Cases of Preeclampsia

Authors: Pandey U*, Kumari A, Lindow SW and Kumar S

DOI: 10.23880/oajg-16000298

Volume 9, Issue 4

Abstract

Introduction: Preeclampsia (PE), a severe pregnancy-related condition, affects various organ systems. PE poses significant risks to maternal and fetal health making careful monitoring and proactive management throughout pregnancy to improve prenatal care and outcomes. Aim: The study aimed to prospectively investigate the relationship between maternal and fetal ABO and Rhesus status and PE Patients and Methods: A case control study was performed with 100 cases of PE (cases) and 200 cases of pregnancies not diagnosed with PE (controls). All cases and controls were women more than 18 years old, having their first baby. In all cases maternal and fetal (umbilical vein) blood samples were taken for ABO and Rhesus C, c, D, E and e status. Direct Coombs (DCT) and Indirect Coombs (ICT) tests were performed on umbilical blood. Results: The total number of cases and controls were 100 and 200, respectively. There was no significant differences in the incidence of any blood group of the ABO and Rhesus systems in both the maternal and fetal specimens between the case and control groups. All Coombs test results (both ICT and DCT) fetal in both PE and control groups were negative. Conclusion: This prospective study of maternal and fetal ABO and Rhesus blood groups indicates that there are no significant differences between cases of PE and controls that did not suffer from PE.

Keywords: Preeclampsia; ABO Blood Group System; Blood Pressure; Proteinuria

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