Macrophage Backpacks: A Novel Strategy for Targeted Brain Drug Delivery

Authors: Sharma A*

DOI: 10.23880/nnoa-16000338

Volume 9, Issue 4

Abstract

The blood-brain barrier (BBB) is a highly selective and protective barrier that separates the brain from the circulatory system. It is composed of tightly packed endothelial cells that prevent most molecules from entering the brain. While this barrier is essential for maintaining the brain’s homeostasis, it also poses a significant challenge for drug delivery to the brain. Most therapeutics are unable to cross the BBB, which limits their efficacy in treating brain diseases. Therefore, there is a need for innovative drug delivery systems that can bypass the BBB and deliver therapeutics to the brain.

Keywords: Drug Delivery; Macrophage Backpacks; Brain Diseases

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