Haematology International Journal (HIJ)
ISSN: 2578-501X
Research Article
Variation in Hematocrit Levels among Chronic Kidney Disease
Patients based on Dialysis Adherence
Abstract
Background: Chronic kidney disease (CKD) is a major global health issue, often progressing to end-stage renal disease (ESRD), requiring dialysis. Anemia is a frequent complication of CKD, and hematocrit levels are used as an indicator of anemia severity. However, the effect of dialysis adherence on hematocrit levels has not been well explored.
Objective: To examine variations in hematocrit levels in CKD patients based on adherence to dialysis treatment.
Methods: This cross-sectional study included 120 CKD patients undergoing hemodialysis. Adherent patients attended at least 90% of prescribed dialysis sessions, while non-adherent patients attended less than 90%. Hematocrit levels were measured through routine blood tests taken within one week prior to participation. Demographic data and dialysis adherence information were gathered from patient records. Statistical analysis was performed using t-tests, Pearson’s correlation, and multivariable linear regression to assess the relationship between dialysis adherence and hematocrit levels, controlling for confounders.
Results: Adherent patients had significantly higher hematocrit levels compared to non-adherent patients (mean = 34.5% vs. 30%, p< 0.001). A strong positive correlation was found between adherence and hematocrit levels (r = 0.71, p < 0.001). Multivariable analysis revealed dialysis adherence as an independent predictor of hematocrit levels (β = 0.63, p < 0.001) after adjusting for age, gender, BMI, and comorbidities.
Conclusion: This study highlights a significant relationship between dialysis adherence and hematocrit levels in CKD patients. Improving adherence to dialysis may help control anemia and enhance clinical outcomes in this population.
Keywords: Chronic Kidney Disease, Hemodialysis, Hematocrit, Dialysis Adherence, Anemia, CKD
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