The Pivotal Role of Conjunctival Microvilli in Ocular Surface Health and Disease and the Transformative Impact of Scanning Electron Microscopy

Authors: Troisi M* , Del Prete S , Troisi S , Marasco D and Costagliola C

DOI: 10.23880/oajo-16000333

Volume 10, Issue 1

Abstract

Conjunctival microvilli, small protrusions of the plasma membrane on the top surface of epithelial cells, play a key role in keeping the eye surface balanced. They help to steady the tear film and keep the epithelium moist. New advances in scanning electron microscopy (SEM) when used with impression cytology (IC), have improved our ability to study these tiny structures. SEM provides detailed 3D images of conjunctival microvilli making it easier to spot early changes in structure linked to eye surface problems like dry eye syndrome, Sjögren's syndrome, and cicatricial pemphigoid. This editorial looks at how important conjunctival microvilli are as signs of eye surface health and highlights the big impact SEM has had on diagnosis, treatment evaluation, and research. We also talk about the hurdles to using SEM in clinics and suggest future directions such as combining SEM with other diagnostic tools and machine learning to make it more accessible. By making the most of SEM's abilities, doctors can diagnose problems earlier, create better treatment plans, and improve results for patients with eye surface disorders.

Keywords: Conjunctival Microvilli; Scanning Electron Microscopy (Sem); Impression Cytology; Ocular Surface; Dry Eye Syndrome

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