Pharmaceutical Drug Regulatory Affairs Journal (PDRAJ)

ISSN: 2642-6315

Research Article

Hydrogen Peroxide Scavenging by Methanolic Extracts of Coriander: An In Vitro Antioxidant Study

Authors: Chaurasia PK* , Yadav M , Kumari S , Nagraj , Sharma N , Bharati SL , Singh S and Jaynath Kumar

DOI: 10.23880/pdraj-16000162

Abstract

Most of the nutraceutical plants, plants associated products and foods are known for their promising antioxidant properties due to the presence of several metabolites like polyphenolic compounds, flavonoids, terpenoids, vitamin C and many other. These molecules have strong tendency to scavenge the free radicals (reactive oxygen species) generated inside our body system due to the various reasons. Out of several methods for the antioxidant activity determination; hydrogen peroxide scavenging activity is an important method. This method has been used to determine the percentage scavenging activity of coriander seeds methanolic extract and coriander leaves methanolic extract for four different concentrations i.e. 100, 200, 300, and 400 μg/mL. Coriander seeds methanolic extracts showed the good level of percentage hydrogen peroxide scavenging activities in the range of 33.67-60.2% while scavenging activities for methanolic extract of coriander leaves were in the range of 47.95-70.61%. Range of scavenging activity for standard ascorbic acid was 65.12-81.35%. Although, extracts showed lower scavenging activity than standard ascorbic acid but result was promising indicating the good antioxidant activities of these extracts. Study demonstrates that methanolic extract of coriander leaves showed higher antioxidant activity (H2O2 scavenging activity) than coriander seeds and thus, coriander leaves are better antioxidant plant source.

Keywords: Hydrogen Peroxide; Percentage Hydrogen Peroxide Scavenging Activity; Antioxidant Activity; Coriander Seeds; Coriander Leaves; Methanolic Extract

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