Spirulina Polypeptides Inhibit the Growth of Human Lung Tumor (H460) Cells

Authors: Gunasekaran NK , Pokharel U , Prabhakaran K , Hall JC , Kumar S and Ramesh GT

DOI: 10.23880/act-16000326

Volume 10, Issue 1

Abstract

Blue-green algae, or cyanobacteria, are some of the oldest organisms on Earth which grow even in extreme conditions. These algae have biologically active compounds which may contribute to the treatment of cancer due to their inhibitory effect against cell cycle and proliferation. Biologically active polypeptides obtained from the filamentous cyanobacterium called spirulina have considerable amounts of proteins and medicinal properties. Spirulina is shown to have benefits across a range of human health indications from malnutrition to anticancer properties. In this research, polypeptides were hydrolyzed from proteins present in spirulina and their anticancer effects were studied using assays such as MTT, Live/Dead, and Cell proliferation in Human Lung Tumor (H460) Cell model.

Keywords: Blue-Green Algae; Cyanobacteria; Spirulina Polypeptides; Anticancer

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