Association of Serum 25-Hydroxyl Vitamin D Deficiency and Idiopathic Presenile Cataract -A Hospital Based Study

Authors: Gupta A and Verma AK

DOI: 10.23880/oajo-16000340

Volume 10, Issue 2

Abstract

Background: Cataract is the leading cause of blindness in India mainly due to age related changes in the lens. Early onset cataract can be visually debilitating having high societal burden requiring early surgical intervention. Identifying modifiablerisk factors can delay or prevent early onset cataractous changes.Aim of the study: The aim of this study was to determine any association between Serum 25-Hydroxyl (25-OH ) Vitamin D Deficiency and Idiopathic Presenile CataractMaterials and Methods: The study was undertaken at Tertiary care hospital in hilly state of India. A detailed medical history was taken and presenile cataract with no identifiable cause was taken in the study group. 67 cataract and 67 controls of bothsexes were examined for 25 hydroxyl vitamin D using the electrochemiluminescence immunoassay method.Observations and Results: Mean 25-OH vitamin D level in cataract patients was 18.91 ± 12.75 ng/mL and median was 18.45 (6 – 95.98) , while in the control group, mean 25-OH vitamin D level was 21.8 ± 13 ng/mL and median was 18.95 ( 4.23 –87.2). There was no statistically significant difference among the cataracts and controls although the mean vitamin D levels were lower in patients with presenile cataract. Female preponderance was seen in the cataract group. Posterior subcapsular cataract was the most common type of morphology seen.Conclusion: In our study serum vitamin D levels were lower than reference range in the idiopathic presenile cataract patients but were not found to be statistically significant.

Keywords: Presenile; Cataract; Vitamin D Deficiency

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