Otolaryngology Open Access Journal (OOAJ)

ISSN: 2476-2490

Research Article

Panorama of Ent Cancers and Literature Review: Epidemiological Profile and Therapeutic Management

Authors: Lawson Afouda S¹* , Gnagbolou A¹ , Avakoudjo F² , Medji S¹ , Séidou F³ , Kouevi A¹ and Adjibabi W¹

DOI: 10.23880/ooaj-16000310

Abstract

Objective: To compile generalized data on head and neck cancers from a leading hospital in our country. Method: A retrospective, descriptive study spanning from January 1, 2010, to December 31, 2020, a period of 11 years, at the CNHU-HKM University ENT Clinic-CCF. The records of patients seen for histologically confirmed head and neck cancer were included. The independent variables were sociodemographic, clinical, paraclinical, and therapeutic. Patients received surgery, chemotherapy, or radiotherapy depending on the histological type and stage of diagnosis. Statistical analysis was performed using Epi Info version 7.2.5 and Microsoft Excel 2021 version 16.0.1 software, and the Kaplan-Meier nonparametric statistical method. Results: We collected 151 cases of malignant tumors, for which 74 records were usable. The incidence of head and neck cancers was 13.72 cases per year. The mean patient age was 41.22 years, ranging from 1 to 75 years. The predominance was male, with a sex ratio of 1.55. Alcohol consumption was the main risk factor in 50% of cases, followed by tobacco use in 23.07%. The consultation time was at least 6 months. The cancer location involves the face (17/74), the oral cavity (12/74), and the larynx (10/74). Histologically, carcinomas (53/74) were predominant. Nearly 60.81% of diagnoses were made at a late stage. From a therapeutic perspective, 49 patients received treatment. Of these, 22 received chemotherapy alone, 19 received surgery alone, and only one patient received radiation. The two-year overall survival rate was less than 60%. Conclusion: Increased awareness and resource mobilization would improve the overall management of head and neck cancers for long-term patient survival.

Keywords: Overview; ENT Cancer; Epidemiology; Treatment

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