Innovations and Challenges in Contemporary Medical Clinical Trials: A Critical Perspective

Authors: Ronaldo M*

DOI: 10.23880/mjccs-16000393

Volume 9, Issue 2

Abstract

The COVID-19 pandemic, now in its fifth year, continues to influence global health research, particularly through clinical trials that have become the cornerstone of understanding and managing the disease. The unprecedented urgency of the pandemic accelerated vaccine development, fostering innovations that are still shaping clinical research in 2025. mRNA vaccines, viral vector platforms, and protein subunit vaccines have evolved to address emerging variants, with adaptive trial designs enabling researchers to modify protocols in real time based on interim findings. These designs have increased trial efficiency, reduced resource wastage, and facilitated rapid deployment of effective interventions, demonstrating a level of flexibility previously uncommon in clinical research.

Keywords: Innovations; Challenges; Contemporary Medical Clinical Trials

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