Interconnected Microbiomes Human Health Within an Environmental Framework

Authors: Sindhu M*

DOI: 10.23880/oajmb-16000320

Volume 10, Issue 4

Abstract

Microbiome research has emerged as a pivotal multidisciplinary field, bridging human health, environmental science, ecology, and biotechnology. At its core, it investigates complex microbial communities—including bacteria, archaea, fungi, and viruses—inhabiting diverse environments, from internal human niches to external ecosystems. In humans, the gut microbiome profoundly influences metabolism, immunity, and disease susceptibility, while environmental microbiomes in soil, water, and built habitats drive nutrient cycling, ecosystem stability, and human exposure to microbes. Advances in high throughput sequencing, multi-omics integration, and computational modelling have unveiled previously hidden microbial diversity and functional potential. This review synthesizes current knowledge, explores methodological and translational advances, highlights therapeutic and environmental applications, and addresses challenges in defining healthy microbiomes, standardizing protocols, and translating findings into clinical and ecological outcomes. Finally, it outlines emerging opportunities for integrative, AI-driven approaches to advance both human and environmental health.

Keywords: Human Gut Microbiome; Environmental Microbiomes; Microbiome Therapeutics; Multi-Omics Integration; Artificial Intelligence in Microbiome Research

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