Cough Syrup or Death Syrup: The Need of Forensic Pharmacovigilance

Authors: Saha A* , Manzungu M and Dutta R

DOI: 10.23880/ijfsc-16000454

Volume 11, Issue 1

Abstract

This article explores the global issue of contaminated and adulterated cough syrups with a particular focus on affected regions such as Asia, Africa, and America. It examines the prevalence and risks associated with different adulterated and contaminated cough syrups, uncovered to contain ethylene glycol and diethylene glycol, toxic substances used as industrial solvents and antifreeze agents, heavy metals, nitrosamine contaminants, active drugs and other contaminants that can be fatal even when taken in small amounts, especially for children under the age of twelve. This has sparked the interest of the World Health organisation in investigating the production and supply chains of medicines with standard quality measures, with assistance from the FDA and the Indian CDSCO health organization in strict regulatory enforcement to ensure drug safety. The article discusses the forensic approach for pharmacovigilance and analysis of such cough syrups in the purview of pharmaceutical toxicology. Moreover, the article discusses collaborative efforts of health organizations worldwide to heighten surveillance, improve inspection protocol and ensure that drugs be tested with utmost rigorousness. This article concludes by emphasizing the need for robust regulatory frameworks to protect public health and prevent future incidents. By addressing this pressing issue, the article aims to inform readers about the dangers of adulterated pharmaceuticals and the ongoing global efforts to mitigate them.

Keywords: Cough Syrup; Over the Counter; Forensic Pharmacovigilance; Glycols; Adulterant; Contaminant

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