Advances in Clinical Toxicology (ACT)

ISSN: 2577-4328

Research Article

Evaluation of Skin Aging Preventive Effects of Cherry Blossom Petal Extracts Through Antioxidant and Anti-Glycation Activities

Authors: Kawaguchi S* , Tabata C , Sasaki YF and Nakamura T

DOI: 10.23880/act-16000333

Abstract

Skin aging progresses due to factors such as aging and UV exposure, with oxidative stress and glycation stress being known to be important contributing factors. Reactive oxygen species (ROS) promote collagen degradation through DNA damage and MMP induction, while advanced glycation end products (AGEs) cause collagen cross-linking and decreased skin elasticity. In this study, to evaluate the potential of Cerasus petal extract as a skin aging prevention material, we examined its antioxidant activity, anti-glycation activity, and melanin production inhibitory effect using B16 cells. As a result, the extract showed high antioxidant and anti-glycation activity, but its melanin production inhibitory effect was limited. These results suggest that Cerasus petal extract may be useful not so much as a whitening material, but rather as a natural material that prevents skin aging through oxidative and glycation stress.

Keywords: Skin Aging; Glycation; Antioxidant; Cerasus Petal

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