Adaptative Immunity, A True New Gene in Ophiocomina Nigra: An Ophuirid Igkappa Gene

Authors: Leclerc M*, Marie Y, Davoult D, Jolly A and de la Grange P

DOI: 10.23880/cclsj-16000117

Volume 3, Issue 1

Abstract

It was shown 32 years ago that the sea star axial organ cells (AO cells) produced a spontaneous cytotoxicity against mouse cancerous cells. Recently, we discovered a sea star Ig kappa gene with immune properties. This gene was inserted in a CMV (cytomegalovirus) and finally in a plasmid called « young » plasmid. The induced« young » protein exerted a spontaneous cytotoxicity against Hela cells (cervix carcinoma cells) and at a weaker degree against dendritic celle, MSC cells.

Keywords:

Ophiocomina Nigra; Ophuirid Igkappa Gene

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