Candida Infection Pathogensis and Host Defensive Mechanism

Authors:

Abdelmoktader A* and Fatma Aboelnaga

Volume 2, Issue 7

Abstract

Candida is a Gram-positive spherical fungi facultative anaerobe, has more than 17 different species and classified into C. albicans and non albicans species. Host response to Candida infection is a complex interplay between innate and adaptive immunity and usually provides a sufficient defense against microbes in healthy individuals but not in immunocompromised ones. Cytokines produced from immune cells also play an important role in epithelial immunity against Candida infection. Candida infection is established by many mechanisms as Adhesins, Invasins, Biofilm, aspartyl proteinases - Haemolysins and Phospholipases.

Keywords:

Candida; PRRs; TLRs; GM; CSF; Adhesins; Invasins; Biofilm; Aspartyl Proteinases; Haemolysins; Phospholipases

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